Treatment with flexible endoscopy of Zenker's diverticulum
an effective and safe technique
DOI:
https://doi.org/10.31837/cir.urug/3.2.1Keywords:
Zenker's diverticulum, flexible endoscopy, endoscopic treatment, cricopharyngeal myotomyAbstract
Background: Treatment of Zenker's diverticulum (DZ) has evolved from open surgery to flexible endoscopy, resulting in lower morbidity and mortality. The endoscopic treatment consists of the cricopharyngealmyotomy using multiple devices.
Aim: The purpose of this study is to show a therapeutic alternative for flexible endoscopy for Zenker's diverticulum, using different cutting instruments.
Methods: We describe a series of cases of patients diagnosed with Zenker's diverticulum treated by endoscopy, between March 2014 and July 2018. Allprocedures were performed by a single endoscopist. Data from endoscopic records werecollected retrospectively and demographic variables, symptoms, technical aspects, complications and follow-up were analyzed.
Results: 12 patients were included, 7 (58%) female, mean age 69 years (range: 53-90). All patients had dysphagia for solids and liquids, 2 patients also had respiratory symptoms. The average size of the diverticula was 3.6 cm. The myotomy was performed with LigaSure in 4 patients, with clutch-cutter in 3 and needle knife in 5 cases. In 11 (91.6%) cases, symptom improvement was obtained, 2 (16%) patients presented recurrence of symptoms during a median follow-up of 9 months. One case (8%) required endoscopoicreintervention to obtain relief of dysphagia. Microperforationwas presented in one patient (8%), which resolved with conservative treatment.
Conclusions:Diverticulotomy through flexible endoscopy was effective and safe for the treatment of DZ, so it should be considered in the therapeutic arsenal of this pathology.
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References
2. Zenker FA, von Ziemssen H. Krankheiten des Oesophagus. In: Handbuch der specielenPathologie und Therapie, Von Ziemssen, H (Ed), FC Vogel, Leipzig 1877. p.1.
3. Siddiq MA, Sood S, Strachan D. Pharyngeal pouch (Zenker’s diverticulum). Postgrad Med J 2001; 77: 506-11.
4. Gagic NM. Cricopharyngealmyotomy. Can J Surg 1983; 26: 47-9.
5. Payne WS. The treatment of pharyngoesophageal diverticulum: The simple and complex. Hepatogastroenterology 1992; 39: 109-14.
6. Mulder CJ, den Hartog G, Robijn RJ, Thies JE. Flexible endoscopic treatment of Zenker's diverticulum: a new approach. Endoscopy 1995; 27: 438-42.
7. Ishioka S, Sakai P, MalufFilho F, Melo JM. Endoscopic incision of Zenker's diverticula. Endoscopy 1995; 27: 433-7.
8. Huberty V, El Bacha S, Blero D, Le Moine O, Hassid S, Devière J. Endoscopic treatment for Zenker’s diverticulum: long-term results (with video). GastrointestEndosc 2013; 77: 701-7.
9. Sakai P, Ishioka S, Maluf-Filho F, Chaves D, Moura EG. Endoscopic treatment of Zenker's diverticulum with an oblique-end hood attached to the endoscope. GastrointestEndosc 2001; 54: 760-3.
10. Fama AF, Moore EJ, Kasperbauer JL.Harmonic scalpel in the treatment of Zenker's diverticulum. Laryngoscope 2009; 119:1265-9.
11. Hondo FY, Maluf-Filho F, Giordano-Nappi JH, Neves CZ,Cecconello I, Sakai P. Endoscopic treatment of Zenker'sdiverti- culum by harmonic scalpel. GastrointestEndosc 2011; 74: 666- 71.
12. PechO, May A, Gossner L, Mayer G, Abdollahnia R, Ell C. Endoscopic therapy for Zenkers's diverticulum by means of argon plasma coagulation. Z Gastroenterol 2002; 40: 517-20.
13. Carrica SA, Martinez H, Correa GJ, Yantorno M, Tufare F, Baldoni FT, et al. Flexible endoscopic treatment for Zenker’s diverticulum: preliminary results in a single center experience in a public hospital in Argentina. Acta GastroenterolLatinoam 2016; 46: 22-9.
14. Anagiotos A, Feyka M, Eslick GD, Lichtenstein T, Henning TD, Guntinas-Lichius O, et al. Long term symptom control after endoscopic laser-assisted diverticulotomy of Zenker's diverticulum. AurisNasusLarynx 2014; 41: 568-71.
15. González N, Viola M, Costa X, Gamba A. Endoscopic treatment of Zenker’s diverticulum by LigaSure scalpel. Endoscopy 2014; 46: Suppl 1 UCTN:E229-30
16. González N, Viola M,Méndez A, Gentile M,Gamba A,Debenedetti D, Duarte A. Tratamiento endoscópico del divertículo de Zenker utilizando LigaSureTM. Acta GastroenterolLatinoam 2017;47(3):169-75.
17. Moreira da Silva BA, Germade A, Pérez Citores L, Maestro Antolin S, Santos F, Sánchez Barranco F, Pérez Millán A, et al. EndoscopicdiverticulotomyusingLigasureTM. GastroenterolHepatol 2017; 40: 80-4.
18. González N, Debenedetti D, Taullard A. Endoscopic retreatment of Zenker's diverticulum using novel endoscopic scissors.The Clutch Cutter device.RevEspEnfermDig. 2017;109(9):669.
19. Akahoshi K, Honda K, Akahane H, Akiba H, Matsui N, Motomura Yet al. Endoscopic submucosal dissection by using a grasping-type scissors forceps: a preliminary clinical study (with video). GastrointestEndosc 2008;67:1128-33.
20. Costamagna G, Mutignani M, Tringali A, Perri V. Treatment of Zenker’s diverticulum with the help of a plastic hood attached to the endoscope. Gastrointestendosc 2002; 56: 611-2.
21. Costamagna G, Iacopini F, Tringali A, Marchese M, Spada C, Familiari P, Mutignani M, Bella A.Flexible endoscopic Zenker’sdiverticulotomy: Cap assisted technique vs. diverticuloscope- assisted technique. Endoscopy 2007; 39: 146-52.
22. Cañete-Gómez J, Ramírez-Plaza CP, Rueda BL, ibáñez-Delgado F, Vázquez-Medina A, Bondía-Navarro JA, Padillo-Ruiz F J. Diverticulectomía y miotomía del cricofaríngeo para el tratamiento del divertículo de Zenker. Presentación de una serie de 33 casos. CirEsp 2012; 90: 233-7.
23. Bonafede JP, Lavertu P, Wood BG, Eliachar I. Surgicaloutcome in 87 patientswithZenker'sdiverticulum. Laryngoscope 1997; 107: 720-5.
24. Gutschow CA, Hamoir M, Rombaux P, Otte JB, Goncette L, Collard JM. Management of pharyngoesophageal (Zenker's) diverticulum: which technique?. Ann ThoracSurg 2002; 74: 1677- 82.
25. Leporrier J, Salamé E, Gignoux M, Ségol P. Zenker's diverticulum: diverticulopexy versus diverticulectomy. Ann Chir 2001; 126: 42-5.
26. Folia M, Chanteret C, Duvillard C, Romanet P. Zenker’s diverticulum: technique and results of endoscopic treatment with Endo-GIA 30 stapler. Rev LaryngolOtolRhinol (Bord) 2008; 129: 101-5.
27. Ishaq S, Hassan C, Antonello A, Tanner K, Bellisario C, Battaglia G, et al. Flexible endoscopic treatment for Zenker's diverticulum: a systematic review and meta-analysis. GastrointestEndosc 2016; 83: 1076-89.e5.
28. Costamagna G, Iacopini F, Bizzotto A, Familiari P, Tringali A, Perri Vet al. Prognostic variables for the clinical success of flexible endoscopic septotomy of Zenker's diverticulum. GastrointestEndosc 2016; 83: 765-73.
29. Brueckner J, Schneider A, Messmann H, Gölder SK. Long-term symptomatic control of Zenker diverticulum by flexible endoscopic mucomyotomy with the hook knife and predisposing factors for clinical recurrence. Scand J Gastroenterol 2016; 51: 666-71.
30. Battaglia G, Antonello A, Realdon S, Cesarotto M, Zanatta L, Ishaq S. Flexible endoscopic treatment for Zenker's diverticulum with the SB Knife. Preliminary results from a single-center experience. Dig Endosc 2015; 27: 728-33.
31. Noguera-Aguilar J, Dolz-Abadía C, Vilella A, Muñoz-Pérez JM, Canaval-Zuleta HJ, Salvatierra-Arrieta L. Transoralendoluminal approach to Zenker's diverticulum using LigasureTM.Early clinical experience. Rev EspEnferm Dig 2014; 106: 137-41.
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